- > However, the study authors emphasize that more research is needed to confirm these mechanisms and determine whether the survival benefit observed in this real-world analysis represents a direct anti-cancer effect or an indirect result of improved metabolic health
Given it’s an observational study, I would bet on the latter. It’s really hard to know you’ve controlled for all confounding factors, and there’s a strong null hypothesis because we know that losing weight can have huge and wide-ranging health benefits.
by surfsvammel
7 subcomments
- I am on GLP-1 (very low dose), and I’ve found that it seems to help me moderate my alcohol consumption as well. Maybe some thing like that could also be contributing to the effect.
- Maybe I'm just an aging cynic, but I'm waiting for the other shoe to drop when it comes to GLP-1s. There have been so many claims of positive benefits that it almost seems too good to be true. With them being so expensive, the producers have every incentive to upsell using any study they can get their hands or money on.
If it's all upside, then I'm happy to be wrong.
- If you eat less your stomach/whole body gets time to relax and repair?
- I am 100% a layman here so apologies if this is a stupid analysis. But I have read that fasting can improve odds and improve side effects during chemo. Would GLP-1 stabilising blood sugar be having the same effect?
- no GLP-1 generics until 2030
lots of people will miss out on benefits, like oh preventing death
our drug system is weird
by agentifysh
4 subcomments
- is there an extract or can you get it from natural food? which have it ?
- I do not like the framing. GLP-1 drugs help people lose weight, and it is the weight loss that lowers death rates in colon cancer[1]. This is making it sound like the drug itself is reducing cancer.
[1] https://link.springer.com/article/10.1007/s12672-025-03902-4
by Willingham
3 subcomments
- [flagged]
Hacker News