FRESH

Hacker News

Stanford Medicine scientists tie lupus to a virus nearly all of us carry

15 points by XzetaU8

by randycupertino

0 subcomment

I've worked in lupus research and one of the things rheumatologists have told me is they see it frequently triggered by the most stressful events in people's lives. So a divorce, eviction, moving, death of a parent or child.
https://hsph.harvard.edu/news/stress-trauma-lupus/
Fortunately great steps have been taken with diagnosis and awareness (it used to not only be hard to find but very stigmatized, lumped in with psycho-somatic disorders like fibromyalgia, long COVID and chronic lyme).
Personally I think the T-cell immune balance research is promising: https://www.prnewswire.com/news-releases/lra-awards-2025-lup...
as well as PARP inhibitors for precision medicine https://clinicaltrials.gov/study/NCT05966480
Car-T for lupus thus far has been a nothingburger (Cabaletta Bio, Nkarta, Kyverna, etc).