My doc put me on 1000mcg of D3 a day for a month after I tested low. I came back in for blood testing and my Calcium levels were extremely high (Not good!). So the doctor ordered me to stop the vitamin D to see what was going on.

As it turns out I have even more lower frequency polymophisms in a gene called CALCA (Calcitonin is a peptide hormone that causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.). So basically since I do not realease a lot of Calcitonin naturally I need to get it from food.

Guess what food is extremely high in Vitamin D3[1] and Calcitonin[2]?

Salmon! I have a genetic history of people that ate a lot of salmon so this makes sense.

Genetics matter people. I will assume that most people who have irish/britsh should be getting their D3 from fatty fish since sunlight is so rare there.

[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC6566758/ [2] https://en.wikipedia.org/wiki/Salmon_calcitonin).

If it were like this, bulk dosing would be expected to be better than nothing (“maximum daytime!!!! Followed immediately by a very long slow sunset at whatever curve it is cleaned up in the body), but it would be better to dose continuously in real time at a level and body location(s) that would simulate the range of sunlight throughout the day.

Can anyone professionally familiar with the research in this area comment?

The summary of that entire conversation is this:

If you ever feel demotivated, defeated or dull just pray to the sun or go into the sunlight.

This message was repeated dozens of times over and over with various metaphors.

I think they were trying to hammer the point that sunlight solves a lot of issues.

Btw not a very revealing article. Basically, saying Vitamin D is important but it's difficult to know how much.

Didn't learn anything more about Vitamin D as the headline suggested.

And how hard is it to make such controlled studies on prison populations (where both sun and food intake is also a known value)? Make it voluntary and give some incentives for those wanting to participate. Can study supplement effects for one or even five years, it's not like they're going anywhere.

That's also a question I have when I hear about diet studies. What's easier than doing such in prison populations? Make it as voluntary as it's for people outside, and there's no ethical issue. We're talking like checking the effect of this or that food or diet style, which they can let different people chose their own. They already eat what they're given anyway, that would be an improvement.

This seems absolutely bonkers. Vitamin D is dirt cheap, and if you can think at all beyond first-order effects, the improvement in immune health alone would likely pay for itself in terms of cost to the healthcare system.

The doctor told me just to pick up some supplements. After a couple weeks I was genuinely surprised how much better I felt. Overall less lethargic. I've been feeling over all just kind of blegh for a long time and it really seems to have helped.

My dad had suggested vitamin d and I didn't take it seriously but he was right.

I really want to meet the people that create these for money and ask them how much it hurt to have their ethics surgically removed.

I’ve talked to people that work at cigarette companies, online gambling, and worse. It’s always fascinating to hear their excuses.

My last blood test showed I was slightly deficient in vitamin D - my doctor recommended a 50 microgram (2000 IU) supplement. My next test to see how well it' working isn't for a few more months.

Also h I chug it down with a solid portion of tran/cod liver oil. D3 is supposedly best ingested with fats.

What? Have these people looked at what Vitamin D costs at the supermarket. If Vitamin D insufficiency has any significant detrimental effects, then 3 bucks of supplements a month surely are cheaper than dealing with the consequences.

If one hour of doctors time costs 200 bucks, then this is enough to pay for FIVE AND A HALF YEARS of Vitamin D supplements.

This seems like a completely insane statement.

Fellow tech people forget hacking your body with innocent pills or having any meaningful effect without sacrifice. Kill your stress, maintain normal weight and have nice relations.

Ugh. It's amazing how incompetent medical systems are. I was also deficient in vitamin D and my doctor wrote a prescription. When I did the math, the cost was something like >$.10 per 1000IU. But if I bought the vitamins from a normal store, I would pay <$.01 per 1000IU. Since a person lacking sunlight only needs 1000IU, the price for giving everyone in the UK Vitamin D would be <$700k/day. And probably much less since most people won't need this high of a dose and bulk quantities would be cheaper.

For healthy people, taking extra vitamins is pointless, but giving them to people who are deficient in vitamins is one of the cheapest health interventions for the benefits.

PSA: if you're feeling off, make sure your doctor checks your various vitamin levels and see if cheap OTC vitamins help.