Right and if that is such a good thing why are those macrophages not always on alert. I smell longterm cancer or similar.

"toll like receptors"

https://pmc.ncbi.nlm.nih.gov/articles/PMC7173040/

https://www.sciencedirect.com/science/article/pii/S135964462...

https://link.springer.com/article/10.1186/s40364-022-00436-7

https://en.wikipedia.org/wiki/Toll-like_receptor

However, it’s my understanding that when the body is in a state of readiness due to its infection (from a cold, flu, etc.) the effects of this (such as fever, inflammation, and general immune response) could potentially could guard the body against other types of infections that the body perhaps doesn’t have resistance to. So while I think a universal vaccine sounds great, I’d try it, and I’d want others I know that have dust allergies, etc. to try it, and because we’ve had friends and family die from the flu, I’m still a little suspicious that this could open the door for other types of disease we’ve not been having to deal with.

there's probably a reason evolution didnt put the immune system on permanent "amber alert" as they call it in the article