by bonsai_spool
0 subcomment
- Here's their preprint from a month ago, in case you can't access the Nature paper: https://www.biorxiv.org/content/10.64898/2026.05.08.723607v1
Nature - https://www.nature.com/articles/s41586-026-10738-7
by ordinaryradical
8 subcomments
- CRISPR is an extremely overhyped approach which found a marketing engine via popular science. There is 1 FDA approved CRISPR therapy as compared to 7 for AAV and 7 for Lentivirus.
Counting all viral vector therapies that have been approved, we’re sitting at 19 approved therapies versus 1 for CRISPR.
I think CRISPR ideas in a lab are just an easy way into the mainstream press, but viral vector delivery is the real future. It just didn’t get the same news cycle, for whatever reason.
- I hope this finally works out. I remember almost exactly ten years ago I got excited about one of these proposed cancer cures, tried to talk about it at lunch with my coworkers, and they laughed at me for believing.
- The article is pretty light on details, but
> Much like other CRISPR therapies, delivery is a critical challenge, i.e., getting the large genome-cutting enzyme to all the targeted cells efficiently.
makes me think this is in vitro so far. So, years to decades away from being available for actual treatment in humans. Still good news.
- Cool. How can I help
by Almondsetat
1 subcomments
- Can anyone point to some resources about how cancers might adapt to CRISPR treatments?
- This is why I hate patents. If CRISPR were put behind a paywall, none of this would have happened. Everything having to be about profit is getting tiring.
by needSomeCoffee
0 subcomment
- Jennifer Doudna again. What an amazing scientist. Wow.
- What economic / political model would cause the society to prioritize this over adtech? It seems so unsettling that brilliant human minds are trying hard, every day, to figure out how to make it impossible to bypass watching ads on YouTube, instead of helping cure cancer.
by sourcegrift
4 subcomments
- Over on reddit people were debating whether cancer should be cured since it disproportionately affects rich people and it made me realise how far reddit has fallen. It's just a botnet now to manipulate elections.
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